This one is for everyone who uses Twitter (which if you do, you should be my friend). Jonathan Snook created his own Twitter App that runs off of the Adobe AIR Platform. It gives you everything you know and love about Twitter right on your desktop. Even though it is in early stages of development, it works pretty good. Giving you all the function that you would have with Twitter on the web, such as reply, and direct message. It’s worth giving it a try, so check it out.